Acetamide
Level 4 — Significant concernsIn Winter's Dictionary
Acetamide is a flavoring — Flavoring agent
What it does
Flavoring agent
Where you'll see it
Flavoring use; FDA reports it is in use
What the research says
JECFA noted available toxicity data indicated it was clearly carcinogenic in both mice and rats, and although the mechanism of tumor formation is unknown, the possibility of gene toxicity cannot be discounted. Has caused liver cancer when given orally to rats.
Regulatory status
- US FDA: EAF
- Notes: JECFA in 2006 found it carcinogenic in mice and rats; agreed it would not be evaluated as a flavoring agent
Sources
- A Consumer's Dictionary of Food Additives (Winter): the available toxicity data for this substance indicated that it was clearly carcinogenic in both mice and rats