Learn → Glossary → other

Advanced Glycation End Products

Level 4 — Significant concerns

Advanced Glycation End Products is a other additive listed in the FDA food-additive database.

Also: AGEs, dietary AGEs, Maillard products, RAGEs (receptors)

Where you'll see it

browned meats, baked goods, processed cheese, dulce de leche, evaporated milk, dark roasted coffee, broiled or grilled foods

What the research says

Dietary AGEs from heat-processed foods are absorbed, bind hepatic RAGE receptors, signal mitochondria to stop burning and store fat, and drive systemic inflammation. Blood RAGEs correlate with vascular damage in adolescents. High dietary AGE intake associated with 30% increased breast cancer risk over 11 years. [metabolical] Dietary AGEs from heat-processed foods are absorbed, bind hepatic RAGE receptors, signal mitochondria to stop burning and store fat, and drive systemic inflammation. Blood RAGEs correlate with vascular damage in adolescents. High dietary AGE intake associated with 30% increased breast cancer risk over 11 years.

Regulatory status

  • Notes: From enrichment source only, not in Winter Dictionary

Sources

  • Metabolical (Lustig) — Chapter 18: those who consumed the most dietary AGEs had a 30 percent increased risk of developing breast cancer