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Amphibolic pathway

Pathway involved in both catabolism and biosynthesis of carbohydrates, fatty acids, or amino acids.

A metabolic pathway that participates in both anabolic and catabolic processes. The tricarboxylic acid (Krebs) cycle is the classic example: it oxidizes acetyl-CoA for energy and also provides intermediates for biosynthesis.

How one textbook covers it

  • Advanced Nutrition and Human Metabolism, 8th ed. (Gropper)Glossary

    A metabolic pathway that participates in both anabolic and catabolic processes. The tricarboxylic acid (Krebs) cycle is the classic example: it oxidizes acetyl-CoA for energy and also provides intermediates for biosynthesis.

Related terms

Anaplerotic reaction, Tricarboxylic acid cycle