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Arcuate nucleus

Subcortical brain region that secretes appetite-enhancing neuropeptide Y and appetite-suppressing melanocortins.

A hypothalamic region central to energy-balance regulation. NPY/AgRP neurons stimulate feeding, while POMC neurons release α-MSH (a melanocortin) to suppress feeding. Targets of leptin, insulin, ghrelin, and PYY signals.

How one textbook covers it

  • Advanced Nutrition and Human Metabolism, 8th ed. (Gropper)Glossary

    A hypothalamic region central to energy-balance regulation. NPY/AgRP neurons stimulate feeding, while POMC neurons release α-MSH (a melanocortin) to suppress feeding. Targets of leptin, insulin, ghrelin, and PYY signals.

Related terms

Anorexigenic, Ghrelin, Leptin, Orexigenic