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DHA

Long-chain omega-3 polyunsaturated fatty acid (22:6n-3) concentrated in brain phospholipids and retinal photoreceptors, essential for neurodevelopment and visual function.

Also: 22:6n-3, DHA, Docosahexaenoic acid

DHA accumulates rapidly in the brain during the third trimester and first two years of life, motivating maternal and infant intake recommendations. DHA is a precursor of D-series resolvins, protectins, and maresins. Vegan diets lack preformed DHA; conversion from ALA is <0.5%. Algal DHA supplements provide a non-fish source. Higher RBC EPA+DHA (Omega-3 Index ≥8%) is associated with lower cardiovascular and all-cause mortality.

How one textbook covers it

  • Modern Nutrition in Health and Disease, 12th ed. — Ch 4: Lipids and Lipid Metabolites

    DHA accumulates rapidly in the brain during the third trimester and first two years of life, motivating maternal and infant intake recommendations. DHA is a precursor of D-series resolvins, protectins, and maresins. Vegan diets lack preformed DHA; conversion from ALA is <0.5%. Algal DHA supplements provide a non-fish source. Higher RBC EPA+DHA (Omega-3 Index ≥8%) is associated with lower cardiovascular and all-cause mortality.

Related terms

ALA, Brain, EPA, Omega-3 fatty acids