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Drug-Nutrient Interaction

Effect of a medication on nutrient absorption, metabolism, or status, or vice versa.

Also: DNI

Examples: warfarin and vitamin K, MAOIs and tyramine, levodopa and high-protein meals, metformin and B12, PPIs and B12/magnesium, antibiotics and calcium/iron. RDNs assess for DNIs during medication reconciliation and adjust the nutrition plan or alert the prescriber. Critical in polypharmacy, especially in older adults and patients on transplant immunosuppressants.

How one textbook covers it

  • Krause and Mahan's Food and the Nutrition Care Process, 16th ed. — Chapter 11

    Examples: warfarin and vitamin K, MAOIs and tyramine, levodopa and high-protein meals, metformin and B12, PPIs and B12/magnesium, antibiotics and calcium/iron. RDNs assess for DNIs during medication reconciliation and adjust the nutrition plan or alert the prescriber. Critical in polypharmacy, especially in older adults and patients on transplant immunosuppressants.

Related terms

Medication Reconciliation, Polypharmacy