Learn Glossary clinical condition

Iron Deficiency

Insufficient iron stores to support normal red blood cell production, the most common nutrient deficiency worldwide.

Also: IDA, Iron-Deficiency Anemia

Progresses through three stages: storage iron depletion (low ferritin), iron-deficient erythropoiesis, and iron-deficiency anemia (low hemoglobin). Causes include inadequate intake, malabsorption (celiac, post-bariatric), chronic blood loss (menstruation, GI bleeding), and increased demand (pregnancy, growth). Heme iron from animal foods is more bioavailable than non-heme iron from plant foods; vitamin C improves non-heme absorption while tannins and calcium inhibit it.

How one textbook covers it

  • Krause and Mahan's Food and the Nutrition Care Process, 16th ed.Chapter 32

    Progresses through three stages: storage iron depletion (low ferritin), iron-deficient erythropoiesis, and iron-deficiency anemia (low hemoglobin). Causes include inadequate intake, malabsorption (celiac, post-bariatric), chronic blood loss (menstruation, GI bleeding), and increased demand (pregnancy, growth). Heme iron from animal foods is more bioavailable than non-heme iron from plant foods; vitamin C improves non-heme absorption while tannins and calcium inhibit it.

Related terms

Anemia, Ferritin, Heme Iron