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Isoeugenol

Level 4Significant concerns

Isoeugenol is a other additive listed in the FDA food-additive database.

Also: FEMA-GRAS flavouring

Where you'll see it

drinks, gum, baked goods (FEMA-GRAS flavouring usage)

What the research says

US National Toxicology Program study found 'clear' evidence isoeugenol caused liver cancer in mice — 80% of male mice treated developed liver tumours. FEMA (the flavour industry self-regulator) kept isoeugenol's GRAS status by arguing US daily per-capita intake is ~2,000x lower than the study dose. [ultra-processed-people] US National Toxicology Program study found 'clear' evidence isoeugenol caused liver cancer in mice — 80% of male mice treated developed liver tumours. FEMA (the flavour industry self-regulator) kept isoeugenol's GRAS status by arguing US daily per-capita intake is ~2,000x lower than the study dose.

Regulatory status

  • Notes: From enrichment source only, not in Winter Dictionary

Sources

  • Ultra-Processed People (van Tulleken)Chapter 15: Dysregulatory bodies: This study found 'clear' evidence that isoeugenol caused liver cancer in mice — 80 per cent of the male mice treated had liver tumours