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Proteomics

Large-scale study of the proteome (expressed proteins) in cells, tissues, and biofluids, typically via mass spectrometry, including identification, quantification, and post-translational modification mapping.

Nutrition proteomics applications include discovery of food-protein-derived plasma biomarkers, identification of allergen epitopes, characterization of post-translational glycation in diabetes (HbA1c is a clinical example), and tissue-specific responses to nutrient interventions. The 12th edition treats proteomics as complementary to metabolomics in objectively profiling diet-disease relationships.

How one textbook covers it

  • Modern Nutrition in Health and Disease, 12th ed.Ch 121: Metabolomics and Proteomics

    Nutrition proteomics applications include discovery of food-protein-derived plasma biomarkers, identification of allergen epitopes, characterization of post-translational glycation in diabetes (HbA1c is a clinical example), and tissue-specific responses to nutrient interventions. The 12th edition treats proteomics as complementary to metabolomics in objectively profiling diet-disease relationships.

Related terms

Metabolomics, Precision nutrition